Master’s/ Doctorate



 1. Mandatory Disciplines



 Bioestatistics (3 Credit Units, 45 Credit Hours)


Professor Eduardo José Melo dos Santos


Syllabus: Provide the student with basic statistical elements applied to biological data analysis. Population and sample. Measures of central tendency. Measures of dispersion. Notions of probability. Normal distribution. Average, variance and standard deviation. Binomial, Poisson, Geometric, Multinomial, Range, Exponential Distribution, etc. Data analysis. Statistic and estimation, Test of significance and limits of confidence, significance of difference between observed averages. One-way analysis of variance. Chi-square test.


Didatic Training (2 Credit Units, 30 Credit Hours)


Professor Adriano Penha Furtado and Professor Délia Aguiar


Syllabus: Students will be encouraged to discuss aspects related to the classroom environment from individual memories. Topics such as methodology, didactics, higher education, specific teaching of infectious and parasitic agents, methods of evaluation and elaboration of lesson plan will be approached from the conflicts generated by the reading of articles, chapters of books and blogs and experiences. The student will be encouraged to present a class of 10 minutes, with the theme of their free choice. In addition, students should exercise in the Graduation classroom, accompanied by a tutor professor.   


Didactic Training II (5 Credits Units, 75 Credit Hours)


Professor Délia Aguiar


Ementa: It aims to guide the students about the methodological and didactic elements (theoretical and practical) in a clear and accessible way, using the techniques / strategies of teaching according to the situations they may encounter in the teaching activity. The discipline counts on an initial theoretical moment of orientation, and a second stage of internship in the classroom, with the supervision of a tutor.


Scientific Methodology and Writing (3 Credit Units, 45 Credit Hours)


Professor Eduardo José Melo dos Santos


Syllabus: Fundamentals of research methods and techniques. Statistical principles and methods and techniques of quantitative research. Methods and techniques of qualitative research. Technical standards for writing academic papers. The research project, elaboration of dissertation and scientific article: structure and textual organization.



2. Elective Disciplines



Amazon and Its Peculiarities: Origin, Water and Biodiversity (2 Credit Units, 30 Credit Hours)


Professor Inocêncio Gorayeb


Syllabus: The subject offers basic knowledge about the Amazon region, explaining the reasons why the diversity is high, including the geological history, the great lake theory, the various biomes, speciation processes, refuges theory, areas of endemism, rainy climate, intertropical convergence zone, trade winds, river types, meadow dynamics, aquifers, soil types, relief and other aspects of the Amazon.


Arbovirology (2 Credit Units, 30 Credit Hours)


Professor Pedro Vasconcelos, Professor Marcio Nunes and Professor Ana Cecília


Syllabus: The subject will present the fundamentals on Arbovirology including clinical-epidemiological aspects of arbovirus and molecular biology. Topics will be discussed on epidemiology and clinical aspects of Arbovirus, basic structure of nucleic acids, organization and characteristics of the arbovirus genome.


Aspects of Parasite-Host Relationship in Helminthology (2 Credit Units, 30 Credit Hours)


Professor Francisco Tiago Melo


Syllabus: This subject aims to establish the knowledge of parasitism by helminths in the context of the parasite-host relationship, aiming to understand the mechanisms of infection, the pathogenic actions caused by parasitism, the immunological reactions of the hosts and the escape mechanisms used by helminths, besides of the role of parasitism in relation to co-infections.


Bacteriology (2 Credit Units, 30 Credit Hours)


Professor Janaina Massafra and Professor Karla Ribeiro


Ementa: The aim of this subject is to promote the study of important groups of bacteria of interest in Medicine and Public Health associated with infectious diseases. Emphasize the structural and physiological properties, nutritional, metabolic and genetic aspects. To address and discuss the mechanisms of virulence and pathogenicity of these agents, as well as to understand how they acquire and disseminate new resistance genes to antimicrobial drugs. Associate acquired theoretical knowledge with advanced molecular biology techniques and approaches, such as new generation sequencing and metagenomics approach, for application in science, technology and public health.


Biomarkers of Infectious and Parasitic Diseases (2 Credit Units, 30 Credit Hours)


Professor Antonio Vallinoto


Syllabus: The field of molecular epidemiology is very promising, with sophisticated techniques being developed to address etiology, genetic susceptibility and mechanisms for disease induction. The use of biomarkers plays a key role in these investigations because their identification can be used to predict disease development and to implement disease prevention programs.


Cell Biology (3 Credit Units, 45 Credit Hours)


Professor Jeannie Nascimento dos Santos


Ementa: The aim of this subject is to review Cell Biology through the perspective of the interaction of infectious and parasitic agents with cells and their cellular components. It addresses general and current aspects of the influence of these agents on the cellular ultrastructure and physiology, integrating knowledge of biochemistry, molecular biology and genetics in the understanding of the changes before the establishment of parasitological and infectious processes.


Cellular and Molecular Aspects of Protozoa-Host Relationship (2 Credit Units, 30 Credit Hours)


Professor Edilene da Silva, Professor Ricardo Machado and Professor Ana Paula Drummond


Syllabus: The main cellular and molecular aspects of the parasite-host relationship, focusing on the main pathogenic protozoa in humans: parasite-host, focusing on the main pathogenic protozoa in humans: Trypanosoma cruzi, Leishmania sp., Toxoplasma gondii, Plasmodium sp., Trichomonas vaginalis , Entamoeba histolytica, Giardia lamblia. It will be given a comprehensive view of Cell Biology and the different strategies used by these organisms to escape host defense mechanisms and their pathogenicity mechanisms.


Cellular Immunology (2 Credit Units, 30 Credit Hours)


Professor Maristela da Cunha


Syllabus: The subject aims to present students with recent advances in the study of the cellular and molecular constituents of the immune system and their interactions in the immune response mediated by the T lymphocytes. Topics related to the differentiation and activation of T lymphocytes, effector mechanisms cellular immune response and regulatory mechanisms of the T lymphocyte-mediated immune response. In this way, the various aspects of the cellular immune response against viruses, bacteria, fungi and parasites of medical interest will be addressed, stimulating discussions about the recent advances in the studies of immunological mechanisms involved in infectious and parasitic diseases.


Data Processing and Analysis (2 Credit Units, 30 Credit Hours)


Professor Luiz Fernando Machado


Ementa: Study of some of the main useful programs to develop public health research, emphasizing the construction of a research questionnaire and the construction, reading and administration of databases.


Desenvolvimento de Vacinas Contra Agentes Infecciosos (3 Credit Units, 45 Credit Hours)


Professor Andrea Rangel


Syllabus: Provide the student with basic and up-to-date subsidies for the development of human vaccines against infectious and parasitic agents through knowledge of the fundamentals of vaccine microbiology and immunology, types of antimicrobial vaccines and the stages involved in their development, as well as new technologies for the development of rational vaccines.


Desenvolvendo Protocolos de Pesquisa (2 Credit Units, 30 Credit Hours)


Professor Ricardo Ishak


Ementa: A practical subject that aims to make students able to (i) develop an understanding of the academic principles of the making of academic projects; (ii) generate a basic research project needed to respond to problems; and (iii) describe the results in the form of an academic, scientific and technological product.


 Epidemiological Geography (2 Credit Units, 30 Credit Hours)


Professor Sandra Lima


Syllabus: The objective of the subject is to introduce notions of the spatial analysis applied to epidemiological information in the area of health: disease mapping, ecological studies and analysis of spatial clusters.


Epidemiologia (4 Credit Units, 60 Credit Hours)


Professor Ricardo Ishak


Syllabus: Presentation of concepts and basic methods in epidemiology and its application in the area of infectious diseases. Discussion on the seroepidemiology tool for the generation of epidemiological information on infectious diseases. The study of the dynamics of infectious diseases in epidemic and inter-epidemic periods. Conceptualization of epidemiological study models and variables used, with topics of discussion that include the calculation of rates, investigation of epidemics, sectional studies, cohort studies, case-control, ecological, errors and confounding factors.


Health and Environment (2 Credit Units, 30 Credit Hours)


Professor Karla Ribeiro


Syllabus: Health, Environment and Sustainable Development: history, evolution and basic concepts; The environmental crisis and its repercussions on human health and the environment; Production processes, consumption and degradation of the environment; Models of the Health-Disease Process: Biomedical and HND; Environmental Health Surveillance; Environmental Health Indicators; Health and Urban and Rural Environment: main environmental impacts; Healthy Cities and Municipalities; Sanitation as a risk factor for health.


Immunogenetics (3 Credit Units, 45 Credit Hours)


Professor Tereza Cristina de Oliveira Corvelo


Syllabus: The aim of this subject is to promote the knowledge of the phylogeny of immunity, the basic aspects of the immune response, highlighting the aspects of the genetics of the immune response that involves the genes of the Principal Histocompatibility Complex, the main events of gene rearrangements that generate specificity to the antibody molecules and TCR and blood group antigens. It is emphasized throughout the course the discussion of articles in the literature that address the description of studies involving the association of polymorphisms in genes of the immune response with the susceptibility or resistance to infectious diseases.


Immunology (2 Credit Units, 30 Credit Hours)


Professor Antonio Vallinoto


Syllabus: Construction of the knowledge about the general characteristics of the immune system and the effects of the activation of the immune response against its self and non-self antigens.


Laboratory Techniques for Light and Electronics Microscopy (2 Credit Units, 30 Credit Hours)


Professor Edilson Matos


Syllabus: Methods of observation after death - Procedures: Fixation, Decalcification. Inclusion / Impregnation, Microtomy. Methods of coloring. Metallic impregnation. Assembly. Ultramicrotomy, Staining, Transmission / scanning electron microscopy observation and interpretation. Accessories of a microscope: photography / video, micrometers of measurement.


Medical Entomoglogy (2 Credit Units, 30 CreditHours)


Professor Inocêncio Gorayeb


Syllabus: The subject aims to promote the study of groups of insects that cause problems and transmit diseases with emphasis in Brazil and the Brazilian Amazon.


Medical Mycology (2 Credit Units, 30 Credit Hours)


Professor Silvia Helena Marques


Syllabus: The purpose of this subject is to offer graduate students basic knowledge about the main fungal infections in our region and in Brazil, including the emerging and the main diagnostic methods used. The discipline focuses especially on epidemiological, clinical, and diagnostic aspects. The course is taught with theoretical classes.


Molecular Basis of Infectious and Parasitic Diseases (2 Credit Units, 30 Credit Hours)


Professor Eduardo José Santos


Syllabus: The subject brings up the genetic modulation of infectious-parasitic diseases. Genetic factors of the host that influence the predisposition or protection of infection by several viral, bacterial, fungal, protozoan and helminthic agents. Additionally, the genetic modulation by the host of the evolution of the disease and response to treatment. This topic will be developed in terms of current knowledge regarding the various genes that are candidates for genetic modulation of these pathologies, as well as the critical exploration of statistical laboratory methods for genealogy and association of case-control studies, discussing the pros and cons of different strategies and approaches Statistics. In addition, databases storing allelic frequencies of immunorelevant genes will be presented.


Molecular Biology (4 Credit Units, 60 Credit Hours)


Professor Evonnildo Gonçalves


Syllabus: At the end of the course, the student should know the theoretical foundations of Molecular Biology, with a view to the structural and functional understanding of the genome in the biological processes of prokaryotes and eukaryotes.


Morphology and Biology of Helminths (3 Credit Units, 45 Credit Hours)


Professors Jeannie Santos and Elane Guerreiro Giese


Syllabus: The discipline aims at the basic training in the taxonomic morphological characterization of Platyhelminthes, Nemata and Acantocephala phyla, of human and veterinary parasitological interest. Instructing on helminth collection and preparation techniques for specific identification and deposition in scientific collections, as well as parasitological diagnostic techniques. In addition to addressing the various aspects of the biology of species of medical interest, related to biological cycles, transmission mechanisms and importance in public health.


Morphology of Microparasites and diseases of the Aquatic Fauna (2 Credit Units, 30 Credit Hours)


Professor Edilson Matos


Syllabus: Study of the morphology of microparasites with the help of light microscopy and electron microscopy. Study of micro parasitic diseases, using parasite morphology, ultrastructure and cytochemistry.


Pharmacology of Resistance to Infectious and Parasitic Anti-Diseases Drugs (2 Credit Units, 30 Credit Hours)


Professor Vanessa Joia


Syllabus: The subject aims to promote the knowledge of drugs of routine use in the treatment and prevention of infectious-parasitic diseases, focusing on their manner of action as well as the mechanisms used by microorganisms in the establishment of resistance that although very similar to some microbial agents and very diversified for others.


Practical Approach in Molecular Biology (2 Credit Units, 30 Credit Hours)


Professor Evonnildo Gonçalves


Syllabus: The aim of this subject is to promote theoretical-practical knowledge in molecular biology techniques such as PCR, RT-PCR, analysis of RFLP, and nucleotide sequencing techniques that allow the development of molecular-level studies of the most diverse types of infectious agents. At the end of the course, the student should know the theoretical and practical fundamentals of the main methods used in Molecular Biology.


Protozoology (2 Credit Units, 30 Credit Hours)


Professor Marinete Póvoa


Syllabus: The subject develops critical thinking and analysis by the presentation and discussion of the most up-to-date articles on the different protozoa, including epidemiological, immunological, biological, phylogenetic, clinical, pathogenic, transmission and control aspects. In addition, parasitological and molecular diagnostic tools, different aspects about vectors and vectoral transmission are objects of discussion. Articles are chosen so that all protozoa and all aspects are covered.


Virology (2 Credit Units, 30 Credit Hours)


Professor Dr. Ricardo Ishak


Syllabus: Study of the morphology, taxonomy, pathogenesis and epidemiology of the major groups of viruses that infect humans. Application of isolation methods and identification of pathogenic viruses and interpretation of the main tests used in viral diagnosis. Introduction to Virology and Molecular Epidemiology.